Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

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Cutaneous Chrome LPG Convertible hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients.In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a Bar Trolley patient receiving long term minocycline.The patient was receiving minocycline as suppression for chronic prosthetic joint infection.Risk factors associated with minocycline-induced cutaneous pigmentation (MICH) will be reviewed.